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Genetic element (GENE)
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last updated: 23 Dec 2025
General information
Methanol expression regulator 1
EN
  • Mxr1
    EN
CS-mxr1-PICPA
EN
Protein coding sequence
No
Donor organism
EN
Characteristics of the protein coding sequence
Methanol expression regulator 1
EN
EN
Additional Information
Mxr1 is a pathway-specific transcription factor that activates genes required for methanol utilization. It coordinates the transcriptional response when methanol is the sole or primary carbon source. Mxr1 binds specific cis-regulatory elements in the promoters of methanol-inducible genes. Its binding leads to strong transcriptional activation under methanol growth conditions. In biotechnology, it is indispensable for AOX1 induction and for the industrial utility of Komagataella pastoris as an expression platform. 
EN
Records referencing this document Show in search
Record type Field Record(s)
Living Modified Organism Introduced or modified genetic element(s) 1
Living Modified Organism Genetic elements construct 1